. B Vitamin Complex and Chemotherapy-Induced Peripheral Neuropathy. Curr Oncol Rep. 2017 Oct 5;19(12):76. doi: 10.1007/s11912-017-0636-z.
[PMID: 28983799] [DOI: 10.1007/s11912-017-0636-z]
Related article: Peripheral neuropathy
Related article: Peripheral neuropathy
Abnormal sensations such as prickling, tingling, itching, burning or cold, skin crawling or impaired sensations–are all called parasthesia. These symptoms usually arise from nerve damage (neuropathy). Continued nerve damage can lead to numbness (lost of sensation) or paralysis (loss of movement and sensation).
Paresthesia is one of the symptoms of Hypervitaminosis-D.
Most people have experienced temporary paresthesia – a feeling of “pins and needles” – at some time in their lives when they have sat with legs crossed for too long or fallen asleep with an arm crooked under their head. It happens when sustained pressure is placed on a nerve. The feeling quickly goes away once the pressure is relieved.
Paresthesia is often felt in the hands, arms, legs, or feet, but can also occur in other parts of the body such as mouth or chest. It may be constant or intermittent.
Paresthesia can be caused by disorders affecting the central nervous system (encephalitis, MS, stroke) or any of the peripheral nerves (carpel tunnel syndrome, atherosclerosis). Peripheral neuropathy is a general term indicating disturbances in the peripheral nerves. It can affect one side of the body (unilateral) or both (bilateral). The peripheral nervous system includes nerves in your face, arms, legs, torso, and some cranial nerves. All of your nerves not located in your central nervous system — which includes the brain and the spinal cord — are peripheral nerves.
Neuropathies may affect just one nerve (mononeuropathy) or several nerves (polyneuropathy). Your nerves provide communication between your brain and your muscles, skin, internal organs and blood vessels. When damaged, your nerves can't communicate properly, and that miscommunication causes symptoms such as pain or numbness.
Neuropathy can result in muscle weakness if it causes reduced nervous stimulation to the muscles. This can occur in any muscle including chest muscles (making breathing difficult) or in the lower extremities (resulting in atrophy and difficulty walking).
There are many causes of peripheral neuropathy 1). It is a fairly common symptom of Th1 diseasesThe chronic inflammatory diseases caused by bacterial pathogens. (autoimmune diseases such as lupus and sarcoidosis) and indicates inflammationThe complex biological response of vascular tissues to harmful stimuli such as pathogens or damaged cells. It is a protective attempt by the organism to remove the injurious stimuli as well as initiate the healing process for the tissue. of the nervous system. Irritation to the nerve can also come from inflammation to the surrounding tissue (such as Rheumatoid Arthritis).
Impaired function and symptoms depend on the type of nerves – motor, sensory, or autonomic – that are damaged. Some people may experience temporary numbness, tingling, and pricking sensations, sensitivity to touch, or muscle weakness. Others may suffer more extreme symptoms, including burning pain (especially at night), muscle wasting, paralysis, or organ or gland dysfunction.
Resolving neuropathy and paresthesia involves identifying and eliminating the underlying cause. The Marshall Protcol is designed to treat the underlying cause of Th1 inflammationThe complex biological response of vascular tissues to harmful stimuli such as pathogens or damaged cells. It is a protective attempt by the organism to remove the injurious stimuli as well as initiate the healing process for the tissue. and thus relieve many of its symptoms. Many MPers report resolution of their paresthesia. Some neuropathy that has persisted for a long time may have caused permanent damage to the nerve cells (neurons) but peripheral nerves have a remarkable ability to regenerate themselves. Only time will tell if the MP will resolve all neuropathy but the evidence so far indicates that it will resolve many paresthesia symptoms and has the potential to effect significant improvement in neuropathies.
Numbness or pin/needles sensation in extremities during sleep
Pins/needles or numbness in extremities suffered during sleep is thought to be due to lymphatic system inflammation and reduced lymph circulation when in a prone position leading to interference with nerve function. Moving the extremity resolves the sensation quickly.
Safety
'Clumsiness' is related to neurological symptoms and these may come and go. Try to be aware of any loss of sensation (or abnormal function) in your hands, feet or ankles. Take precautions. If you are prone to dropping things, avoid cooking or any activities that may be unsafe that day. If your brain can't tell if you are picking up your feet when you walk, steer clear of rugs and obstacles and stay away from stairs.
Now I have very weird tingling sensations, especially in my left fingers. It is like pins and needles when your hand falls asleep. Does anyone know what this is?
I've had varying degrees of numbness, prickling, tingling, in nearly every different part of my body at different stages throughout this healing journey. I just figured it was part of the damaged nervous system being 'rebooted' by the reactivation of my innate immune system. (Not a very scientific explanation, but it helped stop me from freaking out about it!)
Paisleykilt 2013
At one point in my recovery process, I was sweeping away what felt like cobwebs on my elbows and knees. When I realized there weren't any “real cobwebs” I had a good laugh.
Trudy